Gabapentin

What is gabapentin?

Gabapentin is a prescription medicine used to treat a variety of conditions including epilepsy, neuropathic pain (pain related to problems with nerve signals) and anxiety disorders.

Some people use gabapentin recreationally and consequently there is an illicit trade in this drug, including through online pharmacies.

Appearance

Gabapentin comes as white, yellow or orange tablets/capsules. They are normally swallowed, although powder from capsules may be snorted.

UK situation

A letter from the Advisory Council on the Misuse of Drugs sent to the government in January 2016 describes a review of the potential harms associated with the misuse of gabapentin (and the related drug pregabalin). In the UK, pregabalin and gabapentin prescribing has increased by 350% and 150% respectively in 5 years.

In 2013, ten cases of recreational pregabalin abuse were presented to one Emergency Department in Belfast over the course of 2012/13 and the DrugScope Street Drug Survey (2014) reported that most areas covered by the survey highlighted significant use of these drugs, especially among Britain’s opioid-using and prison populations.

One drug worker in York told the survey:

“We’ve seen a big rise in the illicit use of pregabalin and gabapentin. The effects are horrendous and life threatening. People become so heavily intoxicated because they are mixing several drugs at a time. The drugs can reduce the heart rate and if taken with methadone can be extremely dangerous, so we now have to consider whether people are using these drugs when we prescribe methadone.

“Initially we had thought there was a batch of dodgy heroin with Rohypnol in it, but [we found instead that] they were using pregabalin and gabapentin alongside heroin. Often they don’t know what strength capsules they are taking because they look similar. Both drugs are readily available and certainly have a street value attached to them. We have sent a letter to GPs asking them not to prescribe it so much.”

Effects / risks

Gabapentin can produce feelings of relaxation, calmness and euphoria. Some users have reported that the ‘high’ from snorted gabapentin resembles that of a stimulant.

The drug can be dangerous, especially if used with other central nervous system depressants including opioids like heroin and methadone, as well as antidepressants, antihistamines, tranquillisers and alcohol.

The number of fatalities involving these drugs is rising. In October 2015, the National Programme for Substance Abuse Deaths (npSAD) provided the ACMD with a breakdown of deaths associated with pregabalin and gabapentin. In 2013, there were 17 deaths implicated with gabapentin in the UK.

Gabapentin can cause dependence.

For more information on this drug see this advice, aimed at prescribers, from Public Health England (PDF)

The law

Gabapentin is a prescription only medicines and can only be prescribed following a consultation with a doctor.

In January 2016, the ACMD recommended that both pregabalin and gabapentin should be controlled under the Misuse of Drugs Act 1971 as Class C substances.

See also our page on pregabalin

Updated January 2017

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